Antineoplastic multi-drug chemotherapy to sensitize tumors triggers multi-drug resistance and inhibits efficiency of maintenance treatment in glioblastoma cells

Combinations of the well-known antineoplastic agents 5-fluorouracil (5-Fu), cisplatin, and paclitaxel are employed to increase radiotherapy/immunotherapy efficacy against persistent and resistant tumors.However, data remains needed on the hormetic, chronic, and long-term side effects of these aggressive combination chemotherapies.Here we investigat

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Innovative boron nitride-doped propellants

The U.S.military has a need Water Sports Harnesses for more powerful propellants with balanced/stoichiometric amounts of fuel and oxidants.However, balanced and more powerful propellants lead to accelerated gun barrel erosion and markedly shortened useful barrel life.Boron nitride (BN) is an interesting potential additive for propellants that could

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The factor of lend-lease

70 years after the end of World War II there is ongoing debate on the exact role of lendlease in the victory of the USSR, moreover, many Russian Ski de fond - Enfant - Fixations - Classic and foreign authors use the story for the most unseemly purposes, trying to downplay the feat of the Soviet people, to devalue its victims unprecedented in human

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